15 years

inspected CRO / Clinical Research Site




satisfied clients




randomized subjects


biological shipments


subjects in database


CRO / Clinical Research Site

Focuses on early clinical research development & bioequivalence studies

Offers full service studies

Founded in 2002

Company Values





Proven experience (220 conducted studies)

High quality services (EN ISO 9001:2008 obtained in 2009)

State-of-the-art Clinical Research Facility

Highly trained and experienced study team providing accurate, reliable, and consistent data

Respect of project timelines

Company mission

To ensure the safety of the volunteers, and ultimately of patients, the conduct of all  clinical research procedures is performed in strict compliance with the highest international standards


Polish Routine Regulatory Inspection

(The Office for Registration of  Medicinal Products, Medical Devices and Biocidal Products)

Polish Routine Regulatory Inspection

 (The Office for Registration of  Medicinal Products, Medical Devices and Biocidal Products)

FDA inspection
15th anniversary of MTZ Clinical Research
MTZ Clinical Research becomes the member of SCRS

(Society of Clinical Research Sites)

Dr. Teresa Brodniewicz again elected as the President of Good Clinical Practice Society in Poland
ISO recertified till 2018 on the basis of successfully passed audit
MTZ Clinical Research trial service agreement number 200 signed
Launch of new website
Book „ Clinical Trials”

co-authored by 4 employees of MTZ, edited and published by Dr. Teresa Brodniewicz

ISO certification extended to medical services

in MTZ’s Laboratory of Medical Analysis

Registration of Medical Analysis Laboratory of MTZ Clinical Research
Anna Olak – Popko, MD

becomes Clinical Research Site Deputy Director

Anna Dryja, MD, MBA

becomes Clinical Research Site Director

Małgorzata Drop, MSc

becomes Quality Manager and Quality Management System Representative

Closing of MTZ office in Montreal, Canada
Registration of MTZ US Clinical Research, LLC.

a partner company in Massachusetts, USA

Opening of a Pharmacy Unit

equipped with a laminar flow cabinet

Extension of services to include Oncological Products Studies
ISO 9001:2008 Quality Certificate

obtained from DAS CERTIFICATION Ltd. accredited by UKAS

Creation of independent Quality Assurance Department
Teresa Brodniewicz, MSc, PhD

becomes President

MTZ Clinical Research starts acting as CRO

MTZ takes executive decision to focus on early-stage studies.

Extensive renovation of the Clinical Site
Anna Bereda

becomes Quality Assurance Coordinator

Registration of subject database
First Phase I Study
First Bioavailability Study
Katarzyna Jarus-Dziedzic, MD, PhD

becomes Medical Director

MTZ establishes a medical site (NZOZ)

and starts performing clinical trials.

Incorporation of MTZ Clinical Research Sp. z o.o.

Zbigniew Proba, MSc, PhD became President
Teresa Brodniewicz, MSc, PhD became Scientific Affairs and Business Development Director and Vice President


Core Team

All members of the core team have extensive experience in clinical trials conduct either at research institutes, at biopharmaceutical companies or at international CROs in Europe, the US or Canada

All members of the team are obliged to comply with ICH Good Clinical Practice (GCP) requirements, EU, Polish legislation and Company’s Standard Operating Procedures

Teresa Brodniewicz MSc, PhD,

President MTZ Clinical Research Sp. z o.o.

Biochemist in clinical research for over 20 years International experience in research and development President of Polish Society of Good Clinical Practice GCPpl since 2013 Founder, majority owner of MTZ Clinical Research since 2002 Previously Sr. Director at Parexel Int., Warsaw,  Poland, 1997 – 2000 VP and CSO at Haemacure and Scientifc Director at Blood Fractionation Centre, both positions in Montreal, Canada 1982 – 1997

Anna Dryja

Anna Dryja MD MBA,

Clinical Research Site Director

Specializing in clinical oncology, 17 years in clinical trials (experience gained in pharmaceutical companies, CROs and clinical work), PI in several medical experiments, bioequivalence studies and oncological trials With MTZ since 2012


Anna Olak-Popko MD,

Clinical Research Site Deputy Director

Specialist in Internal medicine and anesthesiology Over 15 years experience in clinical trials, bioequivalence and medical experiments, PI in several trials; With MTZ since 2003

Agata Sosnowska

Agata Sosnowska MSc R.N.,

Clinical Operations Director

Experienced in different areas of clinical research Coordinator of several Phase I – III and Bioequivalence studies With MTZ since 2003

Małgorzata Drop

Małgorzata Drop MSc,

Quality Manager

Experience in medicinal product quality for last 16 years Responsible for maintaining and developing ISO 9001 Quality Assurance System and its recertification at MTZ Manager of Quality Department at MTZ since 2011

Zbigniew Proba MSc, PhD,

Director of Financial Affairs

Co-founder MTZ Clinical Research Author and co-author of 23 scientific papers and US patent

Agnieszka Lewczuk

Agnieszka Lewczuk MSc,

Laboratory Affairs Manager

Biotechnologist and laboratory diagnostician with over 8 years of experience in clinical trials Laboratory procedures management in close cooperation with local and central laboratories Regular participation in many external trainings in the field of laboratory medicine and clinical trials With MTZ since 2007

Marta Zakrzewska

Marta Zakrzewska MSc,

Senior Marketing Specialist

Manages business relationships with Clients at MTZ Clinical Research, including assessment of customer needs, meeting quality standards for services, and evaluation of customer satisfaction Vast knowledge in the area of drug development process With MTZ since 2006

MTZ Clinical Research


Operations started in 2002

Conducted above 220 clinical projects

Over 4500 randomized subjects

Full list of Company’s experience – here

List of tested chemical substances BE/BA – here

Summary of Experience in biosimilars- here


Phase graph

Therapeutical area

Therapeutical Area graph


  • (AL) Amyloidosis
  • Acne vulgaris
  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Advanced Carcinoma of the Ovary
  • Alopecia areata
  • Aphthous Ulcers
  • Asthma
  • Atopic Dermatitis
  • Biliary Cancer
  • Cancer pain
  • Chemoteraphy Induced Anemia (CIA)
  • Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL)
  • Chronic Lymphocytic
  • Chronic Myelogenous Leukemia
  • Chronic obstructive pulmonary disease (COPD)
  • Diffuse Large B-Cell Lymphoma (DLBCL)
  • Endometriosis
  • Follicular lymphoma
  • Functional Cognitive Deficiencies
  • Glycemic Index
  • Hemophilia B
  • Hodgkin Lymphoma
  • Idiopathic thrombocytopenic purpura
  • Impaired Hepatic Function
  • Mantle Cell Lymphoma
  • Metastatic breast cancer
  • Metastatic Solid Tumors
  • Multiple Myeloma
  • Myelofibrosis
  • Neuropathic pain
  • Neutropenia
  • Non-Hodgkin Lymphoma
  • Non-small cell Lung Cancer with PD-L1 +
  • Orthostatic Hypotension
  • Osteoarthritis of the hip or knee
  • Pancreatic Cancer
  • Peritoneal cancer
  • Plaque Psoriasis
  • Psoriatic arthritis
  • Rheumatoid arthritis
  • Telangiectasia and lipodystrophy
  • Type 2 diabetes mellitus
  • Uterine fibroids
  • Water retention problems

read more

MTZ Quality


Strict implementation of all current GCP requirements, European Standards and ISO 9001-2008 incorporated into the Quality Management System

Audits and Inspections

During the last 5 years the Company underwent:

25 Audits  (before, during and after the clinical studies)

2 Polish Routine Regulatory Inspection  and one Routine Regulatory Inspection FDA

Inspections focused on the conduct of the bioequivalence trial and Phase III study and concluded in the confirmation of compliance with Good Clinical Practice (GCP), local regulations and the study protocol

Transcelerate BioPharma Inc. Accreditation

MTZ Clinical Research implements for its employees the training program “ICH E6 Good Clinical Practice for Investigators and Site Personnel” accredited by TransCelerate BioPharma Inc.

Membership in SCRS

MTZ Clinical Research is a member of global Society of Clinical Research Sites (SCRS). SCRS is the first trade organization fully dedicated to representing the interests of the clinical research site community. SCRS Certificate